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Best Peptide Serum

Peptide serums for collagen support and firmness. Here are the 5 best picks.

· 5 min read

Our #1 pick

Premium Beauty

SkinMedica

TNS Advanced+ Serum

Under $500

Growth factor + peptide gold standard

Check price on Amazon →

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The short answer
Best peptide serums: SkinMedica TNS Advanced+, Drunk Elephant Protini, Naturium Multi-Peptide Serum (under $50), The Ordinary Multi-Peptide + HA Serum (under $25), and SkinCeuticals Tripeptide-R Neck Repair. Multi-peptide blends work better than single peptides.

Peptide serums signal skin to produce more collagen and elastin. Effective peptides: palmitoyl tripeptide-1, copper tripeptide-1, matrixyl. Pair with retinoid and vitamin C for compounding anti-aging.

Our top 5 picks

2

Drunk Elephant

Premium

Protini Polypeptide Cream

The peptide cream cult

Under $100 Buy →
3

Naturium

Multi-Peptide Moisturizer

Budget multi-peptide at under $50

Under $25 Buy →
4

The Ordinary

Multi-Peptide + HA Serum

Budget multi-peptide at under $25

Under $25 Buy →
5

SkinCeuticals

Premium

Tripeptide-R Neck Repair

Peptide + retinol for neck

Under $150

Frequently asked

Do peptides really work? +

At clinical concentrations, yes. Look for named peptides (palmitoyl tripeptide-1, matrixyl) in top 10 ingredients.